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Why is Allopurinol (Zyloprim) prescribed?

Allopurinol is used for treatment gout, high uric acid's concentrations in the body caused by kidney stones and some cancer medications. Class of medications: xanthine oxidase inhibitors. Allopurinol reduces the uric acid's production in the body. Its high levels may cause kidney stones or gout attacks. Allopurinol prevents gout attacks, but not to treat gout after acute conditions.

How should Allopurinol (Zyloprim) be used?

Allopurinol issued as a oral tablets. It is usually taken 1-2 times a day, preferably after eating. You should remember to take allopurinol around the same time each day. Follow the information on your prescription carefully, and ask your pharmacist or doctor to explain any data you don't understand. Take this medication exactly as directed. Do not take less or more of it or take allopurinol more often than prescribed by your healthcare professional.

Perhabs your physician will start you on a low dose of this medicine and gradually increase allopurinol dose, not more than once a week.

It may take a few months or more before you feel all better properties of allopurinol. During the first few months Zyloprim may increase the quantity of gout attacks, but it will prevent attacks eventually. The doctor may prescribe colchicine or another drugs to prevent gout attacks for the first time you take allopurinol. Continue to take ehis medication even if you feel well. Do not stop taking it your doctor's directions.

Other uses for Allopurinol

Sometimes Zyloprim is used to treat pain (pancreas disease), seizures, certain infections. Also Allopurinol reduces ulcer relapses, improves survival after bypass surgery, prevents rejection of kidney transplants, reduces ulcer relapses. Talk to your specialist about the potential risks of using this medicine for your condition.

Allopurinol may be prescribed for the treatment of other diseases; ask your pharmacist or doctor for more information.

Special precautions before taking allopurinol:

  • tell your healthcare professional if you are allergic to allopurinol or any other drugs.
  • tell your pharmacist and doctor what prescription and otc medications, nutritional supplements, vitamins, and herbal health products you are using. Be sure to mention any of the following: ampicillin (Principen, Polycillin); amoxicillin (Trimox, Amoxil); anticoagulants - warfarin (Coumadin); cancer chemotherapy medicines, for example mercaptopurine (Purinethol) and cyclophosphamide (Cytoxan); chlorpropamide (Diabinese); diuretics; immunesuppressants such as cyclosporine (Sandimmune, Neoral) and azathioprine (Imuran); other drugs for gout: sulfinpyrazone (Anturane) and probenecid (Benemid); tolbutamide (Orinase). The healthcare specialist may need to change the doses of your medicines or monitor you for side effects carefully.
  • tell if you have ever had heart failure or liver or kidney disease.
  • tell if you are pregnant, are breast-feeding or plan to become pregnant. Call your doctor if you become pregnant while taking allopurinol.
  • this medication may make you drowsy. Do not operate machinery or drive a car until you know how allopurinol affects you.
  • alcohol may decrease the effectiveness of allopurinol. While you are taking allopurinol ask your doctor about the safe use of alcoholic drinks.

    What special dietary directions should I follow?

    Drink eight or more glasses of water or other fluids per day while taking allopurinol unless other direction by your doctor.

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    Missing a dose

    Take the missed dose each time as you remember it. If it is almost time for the next allopurinol dose, skip the missed allopurinol dose and continue your regular schedule. Do not use a double quantity to make up for a missed dose.

    What side effects can Allopurinol (Zyloprim) cause?

    This medicine may cause side effects. Tell your doctor about any of these symptoms:

  • diarrhea
  • drowsiness
  • upset stomach

    Some adverse effects can be serious. If you experience any of the following symptoms, call your doctor immediately (these symptoms are uncommon):

  • painful urination
  • blood in the urine
  • swelling of the lips or mouth
  • skin rash
  • loss of appetite
  • irritation of the eyes
  • itching
  • fever, chills, sore throat, and other signs of infection
  • unexpected weight loss

    Allopurinol may cause other adverse effects. Tell your doctor if you have any abnormal problems while taking this medication.

    Storage conditions for Allopurinol (Zyloprim)

    Keep this medicine in the original container, tightly closed, and out of children. Store allopurinol at room temperature and away from excess moisture and heat. Throw away any drugs that is overdue or no longer needed. Talk to a pharmacist about the proper disposal of your medicine.

    You should know some other information.

    Keep all directions with your doctor and the laboratory. Your physician will order certain laboratorial tests to check your body's response to this medication.

    Do not let somebody else take your medication. Ask your healthcare professional any questions about refilling your prescription.


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